Neuromodulator Treatments: Botox and Xeomin Wrinkle-Relaxing Injections

Whether you’re concerned about crow’s feet, frown lines, or even excessive sweating, neuromodulator treatments like Botox and Xeomin play a key role in restoring your skin’s youthful appearance. Learn how neural mechanisms can prevent central nervous system and immune responses that cause muscle contractions, contributing to skin health and elasticity over time.

What Are Neuromodulators?

Neuromodulators are injectable chemicals — often naturally-occurring or mimicking naturally-occurring processes in your body — that relax the facial muscles responsible for dynamic wrinkles. By inhibiting nerve transmission (blocking acetylcholine) to reduce and prevent muscle contractions, these injections contribute to smoother skin. Like other cosmetic injectables, they offer a non-surgical way to enhance your appearance.

Some of the most common neuromodulation therapies include:

Botox: A well-known neuromodulator, Botulinum toxin works by temporarily relaxing the facial muscles that cause wrinkles like crow’s feet, frown lines, and forehead lines. It’s ideal for dynamic wrinkles caused by repeated facial movements.
Xeomin: Similar to Botox, Xeomin is used for smoothing facial wrinkles. As a pure form, it may have a lower risk of allergic reactions.

Neuromodulators vs. Neurotransmitters: What's the Difference

Neuromodulators and neurotransmitters share many similarities, including their involvement in the serotonin system, dopamine system, circulatory system, and central nervous system. However, neurotransmitters are chemicals that transmit signals between nerve cells, while neuromodulators modify these nerve signal transmissions.

In cosmetic treatments, neuromodulators like Botox and Xeomin temporarily block nerve signals to targeted muscles, reducing their activity to diminish the appearance of wrinkles. This targeted approach is distinct from medical neuromodulation techniques used for chronic pain or major depressive disorder, as these treatments typically involve electrical stimulation methods (i.e. spinal cord stimulation or deep brain stimulation).

The Benefits of Neuromodulator Cosmetic Injectables

Remedying Dynamic Wrinkles

Expression lines on your face, including crow’s feet, forehead wrinkles, and frown lines, are caused by repetitive muscle movements and a loss of skin elasticity. By relaxing the muscles responsible for wrinkle formation, Botox and Xeomin can reduce the appearance of existing wrinkles. The result: your skin appears softer and more youthful.

Preventing New Wrinkle Formation

By consistently reducing your muscle’s stress responses with regular neuromodulator treatments, you help slow down the development of new wrinkles. This preventative approach can help maintain smoother skin over time.

Treatment for Excessive Sweating

Neuromodulators aren’t just effective for wrinkle reduction—they are also used to treat hyperhidrosis (excessive sweating). Botox and Xeomin accomplish this by blocking nerve signals to sweat glands, significantly reducing underarm, hand, and foot sweating.

Quick, Non-Surgical Solution

Fast Results with Minimal Downtime

Are You A Good Candidate For Neuromodulator Treatments?

You might be an ideal candidate for neuromodulator cosmetic injectables if you struggle with:

Aging skin
Crow’s feet
Excessive sweating

Frown lines and forehead furrows
Sagging skin
Wrinkles

During a consultation at Lifestyle Med Spa, our specialists will assess your medical history and skin health goals to determine if neuromodulator treatments are suitable for you.

How To Prepare Yourself for Neuromodulator Treatments

If you’re thinking about investing in cosmetic injectables like Botox or Xeomin, following these steps can help ensure a treatment free from negative side effects:

Disclose Health Conditions

Always disclose your medical history and any health conditions you have with your provider. Individuals with muscle disorders should avoid treatment. You should also inform your provider of any infections or muscle weakness near the potential injection site.

Medication Interactions

Notify your practitioner if you are taking antibiotics or medication that impact muscle function. Aminoglycosides are particularly dangerous and can lead to paralysis when paired with Botox treatments.

Previous Surgeries

Inform your provider of any facial surgeries you’ve had in the past, as any changes to your skin and facial muscles can impact the results.

Avoid During Pregnancy or Breastfeeding

Botox is not recommended during these periods.

Limit Alcohol Consumption

Avoid alcohol for at least 24 hours prior to your appointment, as it can increase the likelihood of bruising.

Arrive with a Clean Face

Come to your appointment without makeup to ensure the treatment area is free from contaminants.

What To Expect

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Meet Our Team

Kristina, Family Nurse Practitioner

Kristina is a board-certified Family Nurse Practitioner and earned her Master of Science in Nursing from West Coast University in 2023. She has been a registered nurse since 2016 with a diverse background in the operating room and aesthetics/integrative medicine. Kristina specializes in treatments including intravenous infusions, vitamin therapy, PRP injections, and hydrafacials. She has a passion for helping people lead healthier lives and her interests are rooted in preventive care and believes in a whole-person approach to medical care. In her free time, Kristina enjoys being active and can be found in her off days hiking, exercising in many forms, and spending time with family and friends. See More

Anjmun Sharma, MD

Dr. Anjmun Sharma, MD, is a highly skilled and certified physician specializing in occupational medicine. He is an Aviation Medical Examiner (A.M.E.) and a Designated Civil Surgeon for USCIS. Dr. Sharma is Level II Certified by the Division of Workers' Compensation (DOWC) in Colorado and holds MRO certification. He also serves as an Independent Medical Examiner for the State of Colorado’s Department of Labor & Employment, Division of Workers' Compensation. Dr. Sharma practices at Monument Occupational Medicine, PC, in Colorado Springs, where he provides comprehensive medical services tailored to the needs of his patients. See More

Gisselle Moralles, Medical Assistant

Giselle’s background includes 4 years of dedicated esthetic practice and 5 years of experience as a medical assistant. Her expertise in a range of beauty treatments and a deep understanding of the latest advancements in skin health allows her to be dedicated to helping individuals achieve their unique wellness goals and allows her to approach each client with a comprehensive understanding of their needs. From personalized skin care regimens to innovative treatments like weight loss injections and nutritional booster therapies, she is committed to empowering clients with the knowledge and tools necessary to unlock their full potential. See More

Frequently Asked Questions

How long do Botox and Xeomin results last?

Results from neuromodulator treatments typically last between 3 and 4 months, but are also largely dependent on personal factors. Your natural metabolism, lifestyle, and muscle strength can all play a role in how long results last. Luckily, regular treatments help sustain your desired results.

How often should I get neuromodulator treatments?

We recommend repeating our treatments once every 3 to 6 months, depending on how your body reacts to the injection.

Is there any downtime after cosmetic injectable treatment?

No, neuromodulator cosmetic injectables require little to no downtime. Most patients can return to their day-to-day activities after treatment, but should be advised to avoid strenuous exercise, excessive heat, and lying down for at least 4-6 hours post-treatment to ensure optimal results.

Are Botox and Xeomin injections painful?

No, Botox and Xeomin injections are generally not painful, as most patients report minimal discomfort during the procedure. Numbing cream can also be applied to further reduce discomfort.

How do I know if I should choose Botox or Xeomin?

Both Botox and Xeomin effectively reduce wrinkles, but Xeomin is a purified form of botulinum toxin without accessory proteins. If you’re already taking Botox and have developed a resistance, Xeomin may be a better option. During your consultation, our specialists will help determine which option is best for your needs.

Can neuromodulator treatments be combined with other cosmetic procedures?

Yes! Many patients combine Botox or Xeomin with Plasma Fibroblast Treatments, HydraFacials, and other treatments designed for anti-aging results. Our team can customize a treatment plan to help you achieve your aesthetic goals.

Service Areas

We are based in Agoura Hills, CA, and proudly serve clients in the surrounding areas. Additionally, we offer remote consultations for medical weight loss and are happy to ship injections directly to you. No matter where you are, we’re here to help you achieve your health goals.