GLP-1/GIP Dual Agonist Weight Loss Injections

When you need significant weight loss to manage type 2 diabetes and other health conditions, look no further than dual agonist injectables.

At Lifestyle Med Spa’s Agoura Hills, CA clinic, we use the latest GLP-1/GIP dual receptor agonists to promote weight loss and manage chronic health conditions. Whether you need to stimulate insulin secretion or regulate body weight, GLP-1/GIP dual agonists are a safe and effective way to address diet-induced obesity.

All of our treatments fall under the supervision of board-certified Physician Dr. Michael Rankin MD, who specializes in internal medicine. While we recommend in-person visits when possible, we also offer remote appointments for chronic weight management and can ship GLP-1/GIP injections for those who are a qualified candidate.

Google Reviews

4.8

Based on 48 reviews

Tonya Rose

22:32 09 Dec 25

I’m 35 lbs down and look and feel better than I have in 10+ years. Nicole, Kristina and Erica are the absolute BEST!!! Always kind, helpful, knowledgeable and supportive. 100 stars!

fabiana cavelaris

21:23 03 Dec 25

These are the nicest, most professional, most caring people and most knowledgeable!!!

Ryan Moberly

22:45 13 Nov 25

I have been visiting here for several months getting help with weight loss. The service has been truly amazing, and the results speak for themselves. If you’re looking to partner with a business, that will help you achieve your weight loss goals, I could not recommend anybody more strongly! You will not regret it.

Marcia Tysseling

22:17 10 Sep 25

On this particular visit, I went in for a hydration IV, and staff could not have been more accommodating. There was a sale going on, so the price was very reasonable if not a bargain! The room was comfortable, with snacks and TV and the chairs Were super cozy with a nice soft blanket. I don’t know what more one could expect. Nicole, Erika and Christina always go out of their way with five star service.

Kyla Gordon

17:03 10 Sep 25

Absolutely love the staff and all the services they offer- you won’t regret becoming a client!!

Kelly Franklin

03:41 29 Aug 25

This place is wonderful. Nurse Nicole in particular is a delight! She is super attentive and thorough, she really takes the time to ask questions and give you information. I always feel seen and cared for.

Angela Spangler

23:22 13 Dec 24

Just love these gals and Dr.

Sandy Lawrence

21:20 11 Dec 24

I enjoyed a relaxing hydrofacial from Kristina and I look forward to going back for more. The office was welcoming and Kristina and the staff (Nicole and Katie) were so nice and professional.

Jennifer Radcliff

19:18 10 Dec 24

The team over at Lifestyle has been amazing to work with. They are extremely knowledgeable and friendly and their services are top notch!

Julie Astrachan

01:31 06 Dec 24

I had an absolutely amazing experience at Lifestyle health! From the moment I walked in, I was greeted by the warm and welcoming office staff who made me feel right at home. The atmosphere is calming and pristine, creating the perfect environment for relaxation and rejuvenation.

The range of wellness services offered is impressive — from facials to more specialized treatments like nutrition counseling, weight loss and wellness coaching. The nurse practitioners are incredibly knowledgeable and took the time to listen to all of my concerns, providing personalized recommendations that truly made a difference. I felt like they genuinely cared about my well-being.

Every aspect of my visit was top-notch, and I left feeling refreshed, balanced, and more in tune with my health. Highly recommend Lifestyle Health to anyone looking for a holistic and luxurious wellness experience. I'll definitely be back!

Stephanie Barrus

16:48 05 Dec 24

I have been treated so well and with such kindness here. The staff has been instrumental in helping me reach my goals and I feel amazing. I would recommend this gorgeous, clean, and kind office to family, friends, and strangers! They are simply amazing. Top notch services and people.

Patti Stoddard

20:32 03 Dec 24

When I inquired about medications for weight loss I was warmly welcomed by the staff and immediately assisted. There was no pressure of using their services, instead every question I had was answered. The decision was made and I decided to try the terzipitide. I easily needed to lose 25 lbs. I started off at the lowest dose for a month, then with the help you get from the amazing staff (which is invaluable), I’ve slowly gone up in strength of the medication, my last dose was 7.5mg. I’m on my 15th week and honestly I have never seen 27lbs just fall off so effortlessly. It works that’s all I can say, it really works.

linda pringle

02:33 15 Nov 24

I highly recommend Lifestyle Health Services… I’m on my 3 month there and it’s working like a charm. I feel great and so many of my friends can really see a difference. Annie is awesome she always helps me with scheduling , even when I need to change my appointment last minute Annie is always on top of it. Nicole is amazing too, she really asks me questions about my needs how I’m feeling and always has great suggestions that help me get to the results I want. This is the place if you want results and professional, quality service.

Thomas M. Murphy

18:49 23 Aug 24

When I first started doing research about weight loss shots and medical spas, there was so many sites not willing to be upfront about the cost. Lifestyle health services was the first to layout all out and I appreciated the straightforwardness. I originally told myself that I would go in once a month, ask for my shots in advance to be done at home, but as I got to know the staff I love going in for my weekly appointment. Nurse Nicole is wonderful, very personable and is always ready to answer any questions I might have. The receptionist Annie is the best! She has been most generous with her time and understanding if I've had to change an appointment last minute or even come later in the day. I consider them my ladies! The office is very accommodating and I would and have recommended this office and service to anyone asking how I have lost so much weight this past year.

What Are Dual GIP/GLP-1 Receptor Agonists, and How Do They Work?

GLP-1 and GIP medications are one of the latest and most effective obesity treatments. They mimic naturally occurring glucose dependent insulinotropic polypeptide (GIP) and glucagon‐like peptide‐1 (GLP‐1) hormones. Both play essential roles in glucose-stimulated insulin secretion and other vital components of metabolic health.

By activating both the GIP and GLP-1 receptors—as well as influencing the glucagon receptor—these medications improve insulin sensitivity and energy balance in multiple ways. For example, they stimulate the pancreas to release insulin in response to glucose, reduce excess glucagon secretion, slow gastric emptying, and decrease appetite.

The result: A noticeable body weight reduction and lower blood sugar levels.

Our GLP-1/GIP Dual Agonist Injectable Medications

When deciding whether GLP-1/GIP injection is right for you, it’s important to consider different brand names and their effects. Both medications are injected directly into adipose tissue (fat cells), typically in the abdomen, thigh, or upper arm. Tirzepatide is the most commonly-used brand, and falls under two different subcategories:

Mounjaro: A once-weekly injection with a half-life of approximately 5 days that’s FDA-approved for type 2 diabetes, but also supports weight loss.
Zepbound: Also a once-weekly injection with a half-life of approximately 5 days, but specifically FDA-approved for chronic weight management.

GLP-1/GIP Vs. GLP-1 Receptor Agonists

The primary difference between GLP-1 agonists and GLP-1/GIP dual agonists is the ability to target more than one metabolic pathway. This ability generally makes GLP-1/GIP options cause more blood sugar control and weight loss compared to GLP-1 options. However, GLP-1s also offer well-established research with fewer gastrointestinal side effects.

GLP-1/GIP

How it works: Dual Agonist that activates both GIP and GLP-1 receptors.
Results: In studies, patients experienced a 15-22% reduction in body weight, exceeding what is typically seen with GLP-1 agonists alone.
Brand Names: Available as Mounjaro and Zepbound.

GLP-1

How it works: GLP-1 receptor agonist that only targets the GLP-1 receptor, without the added effects of GIP receptor activation.
Results: Studies show patients losing an average of around 14.9% of their body weight in clinical trials.
Brand Names: Available as Ozempic and Wegovy.

During our initial consultation, we will conduct a comprehensive medical review and decide the best medicine for your body and weight-related comorbidities.

Are GLP-1/GIP Medications FDA approved?

YES – GLP-1/GIP medications like Mounjaro and Zepbound are both FDA approved. Mounjaro was approved in May 2022 for improved glycemic control for patients with type 2 diabetes.

Meanwhile, Zepbound was approved in November 2023 for chronic weight management in adults with obesity, or overweight with one co-morbid condition.

GLP-1/GIP Clinical Trial Weight Loss Results

Across multiple trials, GLP-1/GIP injections consistently led to substantial weight reduction, in the range of 15-26% depending on the dosage and trial conditions.
Comparison to Placebo: the weight loss results were significantly greater than those achieved by placebo groups, underscoring its efficacy in managing obesity and overweight conditions (Lilly Investor Relations).

Potential Side Effects of GLP-1/GIP Injectables

While GLP-1/GIP injections are approved by both the FDA and the American Diabetes Association, it’s important to understand potential adverse events and effects before you start treatment. Mounjaro and Zepbound have similar mild to moderate side effects that often improve over time. Serious allergic reactions are rare but possible.

Prior to starting treatment, Dr. Michael Rankin will review your medical history to ensure the safest and most effective approach for your weight management plan. Please let us know about any history of diabetes, fatty liver disease, cardiovascular disease, kidney failure, cancer, or any other serious or chronic health conditions.

Common Side Effects:

Redness or bruising around the injection site
Nausea
Vomiting
Diarrhea

Abdominal pain
Constipation

Mitigating Side Effects and Osteoporosis Risk

To mitigate potential side effects while treating obesity—including the possibility of decreased muscle mass or bone mineral density as the result of significant weight loss—we recommend:

Starting with a Lower Dose: Dual GIP and GLP-1 medications are powerful, so starting with a lower dose is not only a part of therapeutic efficacy, but can also help your body adjust to gradual effects and increases.
Dietary Adjustments: Eating smaller, more frequent meals and avoiding high-fat or spicy foods can help reduce gastrointestinal discomfort and insulin resistance.
Hydration: Staying hydrated during your treatment is essential, especially if you experience gastrointestinal adverse events like vomiting or diarrhea.
Daily Exercise: Consistent activity like walking, jogging, or resistance training can strengthen bones and counteract both fat accumulation and bone density loss.

Why Choose Lifestyle for Your Weight Loss Journey

At Lifestyle Med Spa, we take obesity, diabetes, and cardiovascular risk factors seriously. Our licensed medical professionals provide comprehensive, personalized injectable treatments that go beyond the spa, providing you with the ongoing support and wellness services you need to reduce food intake, manage physical and mental health, and reach your goals.

Expert Medical Care

Our qualified physicians and nurses conduct thorough medical evaluations that analyze the rate of weight loss, glucose tolerance/production, and more. This ensures the safety and effectiveness of your treatments. We even offer 24/7 emergency support for peace of mind.

Convenient & Personalized Service

Weight loss is an extremely personal journey, and we’re here for you every step of the way. Whether you need specialized diet advice, answers to questions, or additional guidance, our team is dedicated to your success. We’re always on-time, eager, and ready to help, making your visits smooth and stress-free.

Added Health & Wellness Benefits

Our services go beyond weight loss. Enjoy our complimentary B12 skinny injections to boost energy and metabolism, or look into our other wellness services. We can help with anything from Vitamin IV Drips to Personal Training.

Advanced Body Composition Analysis

We include an Evolt 360 Body Composition Scan which provides detailed data about your body through more than 40 measurements. The sophisticated analysis of your body mass and other vital indexes ensures healthy weight loss, and preservation of lean muscle.

Lifestyle Changes for Lasting Results

In addition to GLP-1/GIP treatments, we carefully review your diet and exercise habits to help you maintain weight loss and healthy blood glucose levels. Learn how to incorporate simple, enjoyable lifestyle changes and natural remedies that accelerate weight loss and enhance insulin secretion.

Meet Our Team

Kristina, Family Nurse Practitioner

Kristina is a board-certified Family Nurse Practitioner and earned her Master of Science in Nursing from West Coast University in 2023. She has been a registered nurse since 2016 with a diverse background in the operating room and aesthetics/integrative medicine. Kristina specializes in treatments including intravenous infusions, vitamin therapy, PRP injections, and hydrafacials. She has a passion for helping people lead healthier lives and her interests are rooted in preventive care and believes in a whole-person approach to medical care. In her free time, Kristina enjoys being active and can be found in her off days hiking, exercising in many forms, and spending time with family and friends. See More

Anjmun Sharma, MD

Dr. Anjmun Sharma, MD, is a highly skilled and certified physician specializing in occupational medicine. He is an Aviation Medical Examiner (A.M.E.) and a Designated Civil Surgeon for USCIS. Dr. Sharma is Level II Certified by the Division of Workers' Compensation (DOWC) in Colorado and holds MRO certification. He also serves as an Independent Medical Examiner for the State of Colorado’s Department of Labor & Employment, Division of Workers' Compensation. Dr. Sharma practices at Monument Occupational Medicine, PC, in Colorado Springs, where he provides comprehensive medical services tailored to the needs of his patients. See More

Giselle Morales, Medical Assistant

Giselle’s background includes 4 years of dedicated esthetic practice and 5 years of experience as a medical assistant. Her expertise in a range of beauty treatments and a deep understanding of the latest advancements in skin health allows her to be dedicated to helping individuals achieve their unique wellness goals and allows her to approach each client with a comprehensive understanding of their needs. From personalized skin care regimens to innovative treatments like weight loss injections and nutritional booster therapies, she is committed to empowering clients with the knowledge and tools necessary to unlock their full potential. See More

Lifestyle Med Spa - Our Story

Dr. Kim Barrus, our chief of operations, took Ozempic/Wegovy and lost 22 pounds in four months. He felt more energetic, confident, and healthier.

As he dived into the research, it supported his own experience that these medicines are powerful for looking and feeling better and improving health.

He opened the medical spa to provide these treatments, whether for obesity management or high blood pressure, to his clients from Ventura and Los Angeles counties and throughout Southern California.

As the medical spa has grown, we offer other services to support your health and wellness.

Success Stories

Jaime took Weight Loss Injections and lost 47 lbs in 5 months.

When To Consider Natural Remedies For Weight Loss

Natural remedies may not be as fast or effective as GLP-1/GIP injectables, but whether deployed separately or in tandem with weight loss medications, they can help you make progress toward your goals. Some of the most effective natural remedies with can help with include:

Yerba Mate Tea: Effective for boosting metabolism and fat oxidation, this tea helps increase energy levels and reduce cravings.

Allulose Sweetener: This tasty low-calorie sugar alternative doesn’t spike blood sugar, supporting metabolic health and reducing symptoms of type 2 diabetes.

Optimizing Sleep: Prioritizing a restorative 7–9 hours sleep aids in regulating hormones and controlling appetite, both crucial elements of weight loss.

Nutritional Guidance (Keto Diet): A low-carb (20g or less per day), high-protein, and high-fat diet helps to promote ketosis, a process of efficient fat burning and stable blood-sugar levels. This increased energy intake also supports amino acid balance, helping to preserve lean muscle.

Collagen Peptides: These proteins support muscle maintenance during weight loss, as well as post-weight loss skin elasticity and joint health.

Apple Cider Vinegar: A fantastic natural remedy for improving digestion and reducing appetite, this vinegar helps regulate blood sugar.

GLP-1/GIP Medication: Frequently Asked Questions

Why are GLP-1/GIP medications more powerful than GLP-1s alone?

GLP-1/GIP medications help you lose weight faster and more effectively because they target two hormone pathways instead of one. By activating both the GLP-1 and GIP receptors, they improve insulin secretion and other metabolic functions further than GLP-1 alone. The result is greater blood sugar control and appetite reduction.

In particular, the GIP receptor is known to boost glucose-stimulated insulin secretion and helps balance glucagon secretion, improving how the body handles both high and low blood sugar levels.

Is weight management with GLP-1/GIP medications safe?

Yes, GLP-1/GIP medications are generally safe and well-tolerated. However, like any medication, there may be potential side effects, and it’s important to discuss the risks and benefits with your healthcare provider.

Who is a good candidate for GLP-1/GIP medications?

GLP-1/GIP medications are FDA-approved to treat type 2 diabetes and chronic weight management. Some formulations have also been shown to reduce cardiovascular risk and slow the progression of chronic kidney disease (CKD).

You should be a good candidate for treatment if you have any of these concerns, so long as you don’t have any allergies or conditions that would cause a conflict. We’ll discuss potential conflicts further during your initial consultation.

Can GLP-1/GIP medications be used for weight independent insulin sensitization?

While GLP-1/GIP medications have shown promise in regulating insulin secretion, it’s hard to separate this metabolic benefit from the associated weight loss. If you don’t need to or intend to lose weight, certain natural remedies may be a better option. We’ll work together to find the best possible treatment plan.

How long does it take to see results with GLP-1/GIP medications?

Results can vary, but most individuals see some weight loss within the first few weeks of starting GLP-1/GIP therapy. The full effects may take several months to achieve, but are generally faster than other weight loss injections.

What other weight management strategies should I use alongside GLP-1/GIP therapy?

A balanced diet (healthy fats, protein, fiber, etc.) and regular exercise are important components of any weight management plan. Your healthcare provider may also recommend additional lifestyle changes or other medications to support weight loss.

Do I have to come in every week for GLP-1/GIP weight loss injections?

No, you do not need to come into our office at all. Our doctor can do a remote consultation with you and mail the medicines to you. They are simple to inject yourself. We do follow-up consultations via phone. If your schedule allows, we recommend doing the injections in the clinic because we can accelerate your weight loss based on your tolerance to the medication.

What pharmacies do you get GLP-1/GIP from?

Strive Pharmacy

1275 E Baseline Rd #104
Gilbert, AZ 85233

(480) 626-4366

Service Areas

We are based in Agoura Hills, CA, and proudly serve clients in the surrounding areas. Additionally, we offer remote consultations for medical weight loss and are happy to ship injections directly to you. No matter where you are, we’re here to help you achieve your health goals.